Dosing

Here’s how TECVAYLI® is given

By a doctor or nurse as a monotherapy, which means it is not administered in combination with other treatments for relapsed or refractory multiple myeloma.

As a subcutaneous (under the skin) injection, usually in your stomach area (abdomen), your thigh, or another area of your body.

TECVAYLI® starts with “step-up dosing”

Older woman standing outside near flowers

Actor portrayal.

Step-up dosing is done to reduce your chance of getting Cytokine Release Syndrome (CRS) and/or experiencing neurologic problems by slowly initiating TECVAYLI® starting with a lower dose.

  • Before each step-up dose and your first treatment dose, you will receive medicines to help reduce your risk and/or lessen the severity of CRS, which can be severe or life-threatening
  • You should be hospitalized for 48 hours after each dose in the step-up dosing schedule
  • The amount of TECVAYLI® you receive will be based on your body weight
TECVAYLI® (teclistamab-cqyv) step-up dosing schedule, graphic
TECVAYLI® (teclistamab-cqyv) step-up dosing schedule, graphic

*Step-up dose 2 and/or the first treatment dose may be given between 2 to 4 days after the previous step-up dose.

†Your healthcare provider will decide the number of days to wait between your doses of TECVAYLI® and how many treatments you will receive. Your schedule may change so your healthcare team can manage any side effects.

Continued treatment will be given weekly and may switch to every 2 weeks for certain patients

After step-up dosing, TECVAYLI® is given weekly. If your doctor determines you are responding (a complete response or better) and you continue to respond for at least 6 months, you and your doctor may have the option to change your dosing schedule and give you more time between doses.

TECVAYLI® (teclistamab-cqyv) ongoing dosing schedule, graphic
TECVAYLI® (teclistamab-cqyv) ongoing dosing schedule, graphic

Your healthcare provider will determine if and when your dosing schedule changes based on how you are responding and how long you will receive treatment. After your step-up doses, your healthcare provider will also decide if you need to receive medicines to help reduce your risk of CRS with future doses.

Tell your doctor or healthcare provider about any medications you are currently taking, including prescription medicines, over-the-counter medicines, vitamins, and herbal supplements.

Learn how to get started with TECVAYLI®

Understand the treatment experience

 

Once you and your doctor have decided that TECVAYLI® is right for you, sign up
for TECVAYLI withMe

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TECVAYLI withMe: Personalized 1-on-1 Support

You have access to free, dedicated support. Your Care Navigator is here to help guide you to support solutions throughout your treatment journey so you feel informed and empowered.

Starting a new treatment can be overwhelming, and you may still have questions. We are here to help.

  • Free 1-on-1 Dedicated Care Navigator Support

  • Cost Support Options Regardless of Your Insurance Type

  • Additional Resources and Community Connections

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Call 833-JNJ-wMe1
, Monday through Friday, 8:00 AM–8:00 PM ET.

The support and resources provided by TECVAYLI withMe are not intended to provide medical advice, replace a treatment plan you receive from your doctor or nurse, or serve as a reason for you to start or stay on treatment.