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VOICEOVER: This video is about a patient treated with Tecvayli, teclistamab. Individual results may vary. Tecvayli is a prescription medicine to treat adults with multiple myeloma who have already received at least four treatment regimens, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody, to treat their multiple myeloma and their cancer has come back or did not respond to prior treatment. Tecvayli was approved based on patient responses.
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There are ongoing studies to confirm the clinical benefit of Tecvayli. Data are not yet available to show if Tecvayli improves survival or symptoms. It is not known if Tecvayli is safe and effective in children.
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Selected important safety information: Tecvayli may cause side effects that are serious, life-threatening, or lead to death, including cytokine release syndrome, CRS, and neurologic problems. Tecvayli is available only through the Tecvayli and Talvey Risk Evaluation and Mitigation Strategy, REMS, due to the risk of CRS and neurologic problems. Tecvayli may cause serious side effects, including liver problems, infections, decreased white blood cell counts, and allergic reactions and injection site reactions. Please review the additional Important Safety Information in this video and the full Prescribing Information, including Boxed Warning, for Tecvayli in the link provided. Discuss any questions you have with your doctor.
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JEFF: Hello, my name is Jeff and I have multiple myeloma.
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Nobody ever goes into an injury thinking that it’s something extreme and for me I was – I wasn’t even 50. You know, I'm a 49-year-old guy, super-active, running marathons, great shape, great condition. How could you have something that insidious happen to you?
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RAMONA: Jeff was playing in a baseball game, swung a bat, hit a pop fly. We thought it was a pulled muscle.
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JEFF: It was horrible pain. My regular doctor said we need to give you a MRI. The MRI is what really led to the diagnosis of myeloma.
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RAMONA: And all I heard was oma. I had never heard of myeloma before and it, it shook my foundation, like completely.
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JEFF: When I was diagnosed with cancer, my marathon mentality is what really helped me get my head in the right space of how am I going to do this? And marathon training is exactly that, incremental time. You run a little bit. You lengthen a little farther, a little farther. But you may eventually get to where you want to go.
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I was able to manage, to work through five or six different treatments. I heard about Tecvayli first, casual conversations about promising clinical trials and the bispecifics became the next best choice for me.
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RAMONA: I'm fascinated by the science and loved hearing about how it worked.
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JEFF: So the first day of treatment was the one that had the greatest amount of expectation, and I didn’t know how I would feel, and I just knew what my previous treatments had been, and that’s the reference point. But the experience was as I expected. So now that I'm in the biweekly, as much as we love our nurses and folks that we see every week is a lot, but that’s what your up front’s going to be. But right now, the every-other week has been great. The fact that it’s a subcu shot is also great.
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Making the decision, for me I look at side effects. Those are metrics that, that, you know, that is in the brochure that you’ll have white blood cells that are reduced, neutrophils that are down, your platelets that’ll be reduced.
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For me, I think it’s worth it.
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This is, in my opinion, a unique cancer and cancer environment.
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RAMONA: And in Jeff’s case, I think when he was diagnosed there were four drugs. Now there are more choices and options.
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JEFF: Hope for me is that there’s – there will be more treatment options. So I don’t ever want to look at a calendar and believe that there’s an end date. I want to know that I’ll be able to flip that page and that there’s another month and that there’s another time in that year that I'm going to get there and make it to the hiking trips that we want to do, make it to the interesting places that are yet to be explored on our adventure list. So knowing that there’s more.
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