Dosing
TECVAYLI® is a ready-to-use treatment and is given:
By a doctor or nurse as a monotherapy, which means it is not administered in combination with other relapsed or refractory multiple myeloma (RRMM) therapies.
As a under the skin, usually in your stomach area (abdomen), your thigh, or another area of your body.
Step-up dosing is done to reduce the chance of getting Cytokine Release Syndrome (CRS) and/or experiencing neurologic problems by slowly initiating TECVAYLI® starting with a lower dose.
Before each step-up dose and your first treatment dose, you will receive medicines to help reduce your risk and/or lessen the severity of a serious or life-threatening side effect known as CRS
You should be hospitalized for 48 hours after each dose in the step-up dosing schedule
The amount of TECVAYLI® you receive will be based on your body weight
Step-up dose 2 and/or the first treatment dose may be given between 2 to 4 days after the previous step-up dose.
Your healthcare provider will decide the number of days to wait between your doses of TECVAYLI® and how many treatments you will receive. Your schedule may change so your healthcare team can manage any side effects.
Continued treatment will be weekly dosing and may switch to dosing every 2 weeks for
certain patients
After step-up dosing, TECVAYLI® is given weekly. If your healthcare provider determines you are responding (a complete response or better) and continue to respond for at least 6 months, you may be able to receive your treatment once every 2 weeks.
Your healthcare provider will determine if and when your dosing schedule changes based on how you are responding and how long you will receive treatment. After your step-up doses, your healthcare provider will
also decide if you need to receive medicines to help reduce your risk of CRS with future doses.
Tell your doctor or healthcare provider about any medications you are currently taking, including prescription medicines, over-the-counter medicines, vitamins, and herbal supplements.
